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1

[Methods in Microbiology] Bacterial Pathogenesis Volume 27 || 6.10 Bacterial Exotoxins

Moayeri, Mahtab

Year:

1998

Language:

english

File:

PDF, 1.06 MB

english, 1998

2

Antidotes to anthrax lethal factor intoxication. Part 1: Discovery of potent lethal factor inhibitors with in vivo efficacy

Guan-Sheng Jiao, Seongjin Kim, Mahtab Moayeri, Lynne Cregar-Hernandez, Linda McKasson, Stephen A. Margosiak, Stephen H. Leppla, Alan T. Johnson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 296 KB

english, 2010

3

Antidotes to anthrax lethal factor intoxication. Part 2: Structural modifications leading to improved in vivo efficacy

Seongjin Kim, Guan-Sheng Jiao, Mahtab Moayeri, Devorah Crown, Lynne Cregar-Hernandez, Linda McKasson, Stephen A. Margosiak, Stephen H. Leppla, Alan T. Johnson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 354 KB

english, 2011

4

Lipoprotein biosynthesis by prolipoprotein diacylglyceryl transferase is required for efficient spore germination and full virulence of Bacillus anthracis

Shu Okugawa, Mahtab Moayeri, Andrei P. Pomerantsev, Inka Sastalla, Devorah Crown, Pradeep K. Gupta, Stephen H. Leppla

Journal:

Molecular Microbiology

Year:

2012

Language:

english

File:

PDF, 2.20 MB

english, 2012

5

Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome

Katherine E. Wickliffe, Stephen H. Leppla, Mahtab Moayeri

Journal:

Cellular Microbiology

Year:

2008

Language:

english

File:

PDF, 597 KB

english, 2008

6

Killing of macrophages by anthrax lethal toxin: involvement of the N-end rule pathway

Katherine E. Wickliffe, Stephen H. Leppla, Mahtab Moayeri

Journal:

Cellular Microbiology

Year:

2008

Language:

english

File:

PDF, 318 KB

english, 2008

7

Heat shock inhibits caspase-1 activity while also preventing its inflammasome-mediated activation by anthrax lethal toxin

Tera C. Levin, Katherine E. Wickliffe, Stephen H. Leppla, Mahtab Moayeri

Journal:

Cellular Microbiology

Year:

2008

Language:

english

File:

PDF, 523 KB

english, 2008

8

Spatial localization of bacteria controls coagulation of human blood by 'quorum acting'

Kastrup, Christian J, Boedicker, James Q, Pomerantsev, Andrei P, Moayeri, Mahtab, Bian, Yao, Pompano, Rebecca R, Kline, Timothy R, Sylvestre, Patricia, Shen, Feng, Leppla, Stephen H

Journal:

Nature Chemical Biology

Year:

2008

Language:

english

File:

PDF, 610 KB

english, 2008

9

Novel Repression of the Glucocorticoid Receptor by Anthrax Lethal Toxin

JEANETTE I. WEBSTER, MAHTAB MOAYERI, ESTHER M. STERNBERG

Journal:

Annals of the New York Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 1.25 MB

english, 2004

10

Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain

Guan-Sheng Jiao, Seongjin Kim, Mahtab Moayeri, Devorah Crown, April Thai, Lynne Cregar-Hernandez, Linda McKasson, Banumathi Sankaran, Axel Lehrer, Teri Wong, Lisa Johns, Stephen A. Margosiak, Stephen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 461 KB

english, 2012

11

Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages

Zachary L. Newman, Devorah Crown, Stephen H. Leppla, Mahtab Moayeri

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 457 KB

english, 2010

12

Anthrax Toxin Targeting of Myeloid Cells through the CMG2 Receptor Is Essential for Establishment of Bacillus anthracis Infections in Mice

Shihui Liu, Sharmina Miller-Randolph, Devorah Crown, Mahtab Moayeri, Inka Sastalla, Shu Okugawa, Stephen H. Leppla

Journal:

Cell Host & Microbe

Year:

2010

Language:

english

File:

PDF, 548 KB

english, 2010

13

Cellular and systemic effects of anthrax lethal toxin and edema toxin

Mahtab Moayeri, Stephen H. Leppla

Journal:

Molecular Aspects of Medicine

Year:

2009

Language:

english

File:

PDF, 450 KB

english, 2009

14

The roles of anthrax toxin in pathogenesis

Mahtab Moayeri, Stephen H Leppla

Journal:

Current Opinion in Microbiology

Year:

2004

Language:

english

File:

PDF, 646 KB

english, 2004

15

Anthrax and the inflammasome

Mahtab Moayeri, Inka Sastalla, Stephen H. Leppla

Journal:

Microbes and Infection

Year:

2012

Language:

english

File:

PDF, 306 KB

english, 2012

16

A Bacillus anthracis strain deleted for six proteases serves as an effective host for production of recombinant proteins

Andrei P. Pomerantsev, Olga M. Pomerantseva, Mahtab Moayeri, Rasem Fattah, Cynthia Tallant, Stephen H. Leppla

Journal:

Protein Expression and Purification

Year:

2011

Language:

english

File:

PDF, 1.23 MB

english, 2011

17

Bacillus anthracis Edema Toxin Causes Extensive Tissue Lesions and Rapid Lethality in Mice

Aaron M. Firoved, Georgina F. Miller, Mahtab Moayeri, Rahul Kakkar, Yuequan Shen, Jason F. Wiggins, Elizabeth M. McNally, Wei-Jen Tang, Stephen H. Leppla

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 2.25 MB

english, 2005

18

Quickening the pace of anthrax research: three advances point towards possible therapies

G.Jilani Chaudry, Mahtab Moayeri, Shihui Liu, Stephen H Leppla

Journal:

Trends in Microbiology

Year:

2002

Language:

english

File:

PDF, 104 KB

english, 2002

19

Key tissue targets responsible for anthrax-toxin-induced lethality

Liu, Shihui, Zhang, Yi, Moayeri, Mahtab, Liu, Jie, Crown, Devorah, Fattah, Rasem J., Wein, Alexander N., Yu, Zu-Xi, Finkel, Toren, Leppla, Stephen H.

Journal:

Year:

2013

Language:

english

File:

PDF, 3.55 MB

english, 2013

20

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

von Moltke, Jakob, Trinidad, Norver J., Moayeri, Mahtab, Kintzer, Alexander F., Wang, Samantha B., van Rooijen, Nico, Brown, Charles R., Krantz, Bryan A., Leppla, Stephen H., Gronert, Karsten, Vance,

Journal:

Year:

2012

Language:

english

File:

PDF, 484 KB

english, 2012

21

Anthrax lethal and edema toxins in anthrax pathogenesis

Liu, Shihui, Moayeri, Mahtab, Leppla, Stephen H.

Journal:

Trends in Microbiology

Year:

2014

Language:

english

File:

PDF, 486 KB

english, 2014

22

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

Abrami, Laurence, Brandi, Lucia, Moayeri, Mahtab, Brown, Michael J., Krantz, Bryan A., Leppla, Stephen H., van der Goot, F. Gisou

Journal:

Year:

2013

Language:

english

File:

PDF, 1.55 MB

english, 2013

23

NLRP1a Expression in Srebp-1a-Deficient Mice

Gerlic, Motti, Croker, Ben A., Cengia, Louise H., Moayeri, Mahtab, Kile, Benjamin T., Masters, Seth L.

Journal:

Cell Metabolism

Year:

2014

Language:

english

File:

PDF, 115 KB

english, 2014

24

Raxibacumab augments hemodynamic support and improves outcomes during shock withB. anthracisedema toxin alone or together with lethal toxin in canines

Remy, Kenneth E, Cui, Xizhong, Li, Yan, Sun, Junfeng, Solomon, Steven B, Fitz, Yvonne, Barochia, Amisha V, Al-Hamad, Mariam, Moayeri, Mahtab, Leppla, Stephen H, Eichacker, Peter Q

Journal:

Intensive Care Medicine Experimental

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

25

Late Treatment with a Protective Antigen–Directed Monoclonal Antibody Improves Hemodynamic Function and Survival in a Lethal Toxin–Infused Rat Model of Anthrax Sepsis

Cui, Xizhong, Li, Yan, Moayeri, Mahtab, Choi, Gil H., Subramanian, G. M., Li, Xuemei, Haley, Michael, Fitz, Yvonne, Feng, Jing, Banks, Steven M., Leppla, Stephen H., Eichacker, Peter Q.

Journal:

The Journal of Infectious Diseases

Year:

2005

Language:

english

File:

PDF, 1.37 MB

english, 2005

26

A Heterodimer of a VHH (Variable Domains of Camelid Heavy Chain-only) Antibody That Inhibits Anthrax Toxin Cell Binding Linked to a VHH Antibody That Blocks Oligomer Formation Is Highly Protective in an Anthrax Spore Challenge Model

Moayeri, Mahtab, Leysath, Clinton E., Tremblay, Jacqueline M., Vrentas, Catherine, Crown, Devorah, Leppla, Stephen H., Shoemaker, Charles B.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 3.27 MB

english, 2015

27

Sublethal Doses of Bacillus anthracis Lethal Toxin Inhibit Inflammation with Lipopolysaccharide and Escherichia coli Challenge but Have Opposite Effects on Survival

Cui, Xizhong, Li, Yan, Li, Xuemei, Haley, Michael, Moayeri, Mahtab, Fitz, Yvonne, Leppla, Stephen H., Eichacker, Peter Q.

Journal:

The Journal of Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 1023 KB

english, 2006

28

Monoclonal Antibody Therapies against Anthrax

Chen, Zhaochun, Moayeri, Mahtab, Purcell, Robert

Journal:

Year:

2011

Language:

english

File:

PDF, 171 KB

english, 2011

29

Bacillus anthracis Edema and Lethal Toxin Have Different Hemodynamic Effects but Function Together to Worsen Shock and Outcome in a Rat Model

Cui, Xizhong, Li, Yan, Li, Xuemei, Laird, Michael W., Subramanian, Mani, Moayeri, Mahtab, Leppla, Stephen H., Fitz, Yvonne, Su, Junwu, Sherer, Kevin, Eichacker, Peter Q.

Journal:

The Journal of Infectious Diseases

Year:

2007

Language:

english

File:

PDF, 1.12 MB

english, 2007

30

Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome

Levinsohn, Jonathan L., Newman, Zachary L., Hellmich, Kristina A., Fattah, Rasem, Getz, Matthew A., Liu, Shihui, Sastalla, Inka, Leppla, Stephen H., Moayeri, Mahtab, Young, John A. T.

Journal:

Year:

2012

Language:

english

File:

PDF, 404 KB

english, 2012

31

Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment

Moayeri, Mahtab, Crown, Devorah, Newman, Zachary L., Okugawa, Shu, Eckhaus, Michael, Cataisson, Christophe, Liu, Shihui, Sastalla, Inka, Leppla, Stephen H., Deretic, Vojo

Journal:

Year:

2010

Language:

english

File:

PDF, 1.35 MB

english, 2010

32

The Heart Is an Early Target of Anthrax Lethal Toxin in Mice: A Protective Role for Neuronal Nitric Oxide Synthase (nNOS)

Moayeri, Mahtab, Crown, Devorah, Dorward, David W., Gardner, Don, Ward, Jerrold M., Li, Yan, Cui, Xizhong, Eichacker, Peter, Leppla, Stephen H., Koehler, Theresa

Journal:

Year:

2009

Language:

english

File:

PDF, 7.29 MB

english, 2009

33

Susceptibility to Anthrax Lethal Toxin-Induced Rat Death Is Controlled by a Single Chromosome 10 Locus That Includes rNlrp1

Newman, Zachary L., Printz, Morton P., Liu, Shihui, Crown, Devorah, Breen, Laura, Miller-Randolph, Sharmina, Flodman, Pamela, Leppla, Stephen H., Moayeri, Mahtab, Koehler, Theresa

Journal:

Year:

2010

Language:

english

File:

PDF, 627 KB

english, 2010

34

Efficient Neutralization of Anthrax Toxin by Chimpanzee Monoclonal Antibodies against Protective Antigen

Chen, Zhaochun, Moayeri, Mahtab, Zhou, Yi‐Hua, Leppla, Stephen, Emerson, Suzanne, Sebrell, Andrew, Yu, Fujuan, Svitel, Juraj, Schuck, Peter, St. Claire, Marisa, Purcell, Robert

Journal:

The Journal of Infectious Diseases

Year:

2006

Language:

english

File:

PDF, 222 KB

english, 2006

35

Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii

Cirelli, Kimberly M., Gorfu, Gezahegn, Hassan, Musa A., Printz, Morton, Crown, Devorah, Leppla, Stephen H., Grigg, Michael E., Saeij, Jeroen P. J., Moayeri, Mahtab, Sassetti, Christopher M.

Journal:

Year:

2014

Language:

english

File:

PDF, 903 KB

english, 2014

36

Anthrax Pathogenesis

Moayeri, Mahtab, Leppla, Stephen H., Vrentas, Catherine, Pomerantsev, Andrei, Liu, Shihui

Journal:

Annual Review of Microbiology

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

37

Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

Moayeri, Mahtab, Tremblay, Jacqueline M., Debatis, Michelle, Dmitriev, Igor P., Kashentseva, Elena A., Yeh, Anthony J., Cheung, Gordon Y. C., Curiel, David T., Leppla, Stephen, Shoemaker, Charles B.,

Journal:

Clinical and Vaccine Immunology

Year:

2016

Language:

english

File:

PDF, 765 KB

english, 2016

38

148. Variable fragment of heavy chain antibody (VHH)–based neutralizing agents (VNAs) as unconventional and versatile therapeutics for toxin-mediated diseases

Mukherjee, Jean, Tremblay, Jacque, Sheoran, Abhineet, Schmidt, Diane, Vance, David J., Mantis, Nicholas J., Moayeri, Mahtab, Leppla, Stephen H., Dmitriev, Igor, Curiel, David T., Tzipori, Saul, Shoema

Journal:

Year:

2015

Language:

english

File:

PDF, 56 KB

english, 2015

39

Delayed treatment with W1-mAb, a chimpanzee-derived monoclonal antibody against protective antigen, reduces mortality from challenges with anthrax edema or lethal toxin in rats and with anthrax spores in mice

Altaweel, Laith, Chen, Zhaochun, Moayeri, Mahtab, Cui, Xizhong, Li, Yan, Su, Junwu, Fitz, Yvonne, Johnson, Syd, Leppla, Stephen H., Purcell, Robert, Eichacker, Peter Q.

Journal:

Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

40

Norepinephrine increases blood pressure but not survival with anthrax lethal toxin in rats*

Li, Yan, Cui, Xizhong, Su, Junwu, Haley, Michael, Macarthur, Heather, Sherer, Kevin, Moayeri, Mahtab, Leppla, Stephen H., Fitz, Yvonne, Eichacker, Peter Q.

Journal:

Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

41

Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model*

Sherer, Kevin, Li, Yan, Cui, Xizhong, Li, Xuemei, Subramanian, Mani, Laird, Michael W., Moayeri, Mahtab, Leppla, Stephen H., Fitz, Yvonne, Su, Junwu, Eichacker, Peter Q.

Journal:

Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 1.15 MB

english, 2007

42

A diverse set of single-domain antibodies (VHHs) against the anthrax toxin lethal and edema factors provides a basis for construction of a bispecific agent that protects against anthrax infection

Vrentas, Catherine E, Moayeri, Mahtab, Keefer, Andrea B, Greaney, Allison J, Tremblay, Jacqueline, O'Mard, Danielle, Leppla, Stephen H, Shoemaker, Charles B

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 4.83 MB

english, 2016

43

In vivo characterization of an Hfq protein encoded by the Bacillus anthracis virulence plasmid pXO1

Keefer, Andrea B., Asare, Eugenia K., Pomerantsev, Andrei P., Moayeri, Mahtab, Martens, Craig, Porcella, Stephen F., Gottesman, Susan, Leppla, Stephen H., Vrentas, Catherine E.

Journal:

BMC Microbiology

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

44

Shock and Lethality with Anthrax Edema Toxin in Rats are Associated with Reduced Arterial Responsiveness to Phenylephrine and are Reversed with Adefovir

Suffredini, Dante Alexander, Li, Yan, Xu, Wanying, Moayeri, Mahtab, Leppla, Stephen H, Fitz, Yvonne, Cui, Xizhong, Eichacker, Peter Q.

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

45

Small molecule inhibitors of anthrax edema factor

Jiao, Guan-Sheng, Kim, Seongjin, Moayeri, Mahtab, Thai, April, Cregar-Hernandez, Lynne, McKasson, Linda, O'Malley, Sean, Leppla, Stephen H., Johnson, Alan T.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 748 KB

english, 2017

46

Anthrax immune globulin improves hemodynamics and survival during B. anthracis toxin-induced shock in canines receiving titrated fluid and vasopressor support

Suffredini, Dante A., Cui, Xizhong, Jaswal, Dharmvir, Remy, Kenneth E., Li, Yan, Sun, Junfeng, Solomon, Steven B., Fitz, Yvonne, Moayeri, Mahtab, Leppla, Stephen, Eichacker, Peter Q.

Journal:

Intensive Care Medicine Experimental

Year:

2017

Language:

english

File:

PDF, 1.65 MB

english, 2017

47

Inflammasomes in livestock and wildlife: Insights into the intersection of pathogens and natural host species

Vrentas, Catherine E., Schaut, Robert G., Boggiatto, Paola M., Olsen, Steven C., Sutterwala, Fayyaz S., Moayeri, Mahtab

Journal:

Veterinary Immunology and Immunopathology

Year:

2018

Language:

english

File:

PDF, 582 KB

english, 2018

48

Role of N-Terminal Amino Acids in the Potency of Anthrax Lethal Factor

Gupta, Pradeep K., Moayeri, Mahtab, Crown, Devorah, Fattah, Rasem J., Leppla, Stephen H., Antopolsky, Maxim

Journal:

Year:

2008

Language:

english

File:

PDF, 322 KB

english, 2008

49

Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions

D’Agnillo, Felice, Williams, Matthew C., Moayeri, Mahtab, Warfel, Jason M., Brandner, Johanna M.

Journal:

Year:

2013

Language:

english

File:

PDF, 7.36 MB

english, 2013

50

Anthrax Edema Factor Toxicity Is Strongly Mediated by the N-end Rule

Leysath, Clinton E., Phillips, Damilola D., Crown, Devorah, Fattah, Rasem J., Moayeri, Mahtab, Leppla, Stephen H., Boyaka, Prosper N

Journal:

Year:

2013

Language:

english

File:

PDF, 744 KB

english, 2013